CJC-1295 DAC (20mg)

Original price was: $110.00.Current price is: $62.00.

CJC-1295 is a synthetic analogue of growth hormone releasing hormone (GHRH) that increases plasma levels of growth hormone and insulin-like growth factor 1 (IGF-1). DAC is an additive moiety that prolongs the plasma half-life of CJC-1295.


  • 1 sterile 10ml multi-dose vial
  • Active ingredient: CJC-1295 with DAC at 2mg/ml
  • Diluted in sterile bacteriostatic saline
  • Clear, injectable solution
  • Packaged in pharmaceutical-grade glass vial with tamper-evident seal
  • For subcutaneous administration only

CJC-1295 with DAC (Drug Affinity Complex) is a long-acting analog of Growth Hormone Releasing Hormone (GHRH 1-29), engineered for sustained stimulation of endogenous growth hormone (GH) and insulin-like growth factor-1 (IGF-1) release. The inclusion of DAC significantly extends its half-life from minutes (as seen in native GHRH) to up to 8–10 days, allowing for less frequent dosing and more stable GH pulsatility.

CJC-1295 is often used to support:

  • Anti-aging and vitality protocols
  • Muscle recovery and lean mass development
  • Fat metabolism and body recomposition
  • Sleep quality, cognition, and skin health

Its unique structure enhances binding to albumin, reducing renal clearance and enabling prolonged biological activity.

CJC-1295 functions as a GHRH analog, binding to GHRH receptors in the anterior pituitary to stimulate endogenous growth hormone release. The addition of DAC extends its biological half-life by promoting covalent binding to albumin and reducing proteolytic degradation.

Key physiological actions include:

  • Increased amplitude and frequency of GH pulses
  • Subsequent elevation of circulating IGF-1 levels
  • Stimulation of protein synthesis and lipolysis
  • Promotion of lean muscle gain and fat metabolism
  • Improved cellular repair and collagen production

CJC-1295 with DAC does not inhibit the normal negative feedback mechanisms of GH secretion, preserving natural pulsatility while amplifying its effect.

CJC-1295 with DAC is generally well tolerated, with most side effects being mild and transient.

Reported side effects may include:

  • Mild water retention or bloating
  • Temporary numbness or tingling (paresthesia)
  • Fatigue or lightheadedness
  • Headache or flushing
  • Mild injection site irritation

Higher doses may lead to increased hunger or minor joint discomfort due to elevated IGF-1 levels.

Potential Benefits:
  • Enhanced muscle growth and recovery
  • Improved fat metabolism and body composition
  • Better sleep quality via increased GH output during deep sleep
  • Increased skin elasticity and collagen repair
  • Support for joint and connective tissue recovery

May improve cognitive clarity and mood

⚠️ Possible Side Effects:
  • Water retention or slight weight fluctuation
  • Numbness or tingling (especially in hands or feet)
  • Headaches or flushing after injection
  • Rare: increased hunger or slight insulin resistance with long-term high doses
  • Hypersensitivity to peptide-based medications
  • Use with caution in individuals with active malignancies, as elevated GH/IGF-1 may potentially stimulate tumor growth
  • Not recommended for individuals with uncontrolled diabetes, acromegaly, or pituitary adenomas
  • Monitor IGF-1 levels and fasting glucose during prolonged use
  • Avoid use with concurrent GH therapy unless medically directed
  • May have additive effects with GH secretagogues such as Ipamorelin or MK-677
  • No direct drug-drug interactions reported
  • Avoid concurrent use with exogenous GH unless under physician supervision due to possible feedback suppression

There is no clinical safety data available for the use of CJC-1295 in pregnant or breastfeeding individuals. Due to the growth-promoting and hormonal effects of the compound, it is not recommended during pregnancy or lactation.

CJC-1295 is not approved for pediatric use. While it mimics natural GHRH and may theoretically benefit growth hormone-deficient children, it should only be considered under strict endocrinological supervision in such cases. Unsupervised use in children is contraindicated.

CJC-1295 (with or without DAC) is not FDA-approved as a therapeutic drug. It remains under clinical investigation and is available through compounding pharmacies and research outlets. It is not approved as a treatment for GH deficiency or related conditions.

  1. Teichman SL, et al. (2006). "Pharmacokinetics of CJC-1295, a long-acting GHRH analog." Journal of Clinical Endocrinology & Metabolism.
  2. Ip C, et al. (2009). "GH and IGF-1 responses to CJC-1295 with DAC." Clinical Pharmacology & Therapeutics.
  3. Meinhardt U, et al. (2010). "Long-acting GHRH analogs in metabolic health." Hormone Research in Paediatrics.
  4. Bartke A. (2011). "The role of GH in aging and longevity." Endocrine Reviews.
  5. Liu NA, et al. (2021). "Clinical applications and risks of GHRH analogs." Trends in Endocrinology & Metabolism.
Categories: , Tag: